What Greenbrook TMS NeuroHealth offers for ketamine treatment

Greenbrook TMS NeuroHealth is a network of clinics that provides ketamine infusion therapy as an in-office medical treatment. The company operates multiple locations across the United States and administers ketamine under medical supervision in a clinical setting, rather than as a take-home medication. Each infusion session takes place at a Greenbrook facility where a healthcare provider monitors you during and after the procedure.

Greenbrook's ketamine program is structured around a series of infusions spaced over several weeks. The exact number of sessions and the spacing between them depends on your individual treatment plan, which a doctor at the clinic determines during your initial consultation. Unlike some other ketamine delivery methods, Greenbrook's model requires you to travel to a physical location for each dose.

The company markets its ketamine service primarily to people with treatment-resistant depression — depression that has not responded to at least two different antidepressant medications tried at adequate doses. Some Greenbrook locations also treat other conditions, though depression remains the primary focus across their network.

Key Takeaways

  • Greenbrook TMS NeuroHealth administers ketamine infusions at physical clinic locations, with each session lasting several hours including monitoring time.
  • Treatment typically involves multiple infusions scheduled over several weeks, with the exact schedule determined by the doctor overseeing your care.
  • You will need to arrange transportation to and from each appointment, as you cannot drive yourself when ready after receiving an infusion.
  • Greenbrook locations vary by region, so availability depends on whether a clinic operates near you and whether they are currently accepting new patients.
  • Insurance coverage and out-of-pocket costs differ by plan and location, so contacting Greenbrook directly is necessary to learn what you would pay.

How a Greenbrook ketamine infusion session works

When you arrive for your first appointment, a Greenbrook clinician will review your medical history, current medications, and the symptoms you are experiencing. This consultation determines whether ketamine infusion is appropriate for you and establishes your baseline. The doctor will also explain what to expect during the infusion itself and answer questions about the procedure.

On the day of your infusion, you will sit or recline in a treatment room while a nurse or technician places an IV line. The ketamine is administered intravenously over a set period — typically 40 minutes to an hour, though timing varies by clinic protocol. During the infusion, you remain awake but may experience dissociation, a feeling of detachment from your body or surroundings. A staff member stays with you throughout the procedure to monitor your vital signs and may support your safety.

After the infusion ends, you enter a recovery period lasting 30 minutes to an hour. During this time, you rest in the clinic while the effects of the ketamine wear off. You cannot drive or operate machinery for the remainder of the day, so you must arrange for someone to pick you up or use a rideshare service. Most people are able to return to normal activities the following day, though some experience grogginess or mild dissociation for a few hours after leaving the clinic.

Treatment schedule and duration

Greenbrook's standard ketamine protocol involves an induction phase followed by maintenance sessions. The induction phase typically consists of 6 infusions given over 2 to 3 weeks — often twice per week or on an every-other-day schedule. After the induction phase, your doctor may recommend maintenance infusions spaced further apart, such as once every 1 to 2 weeks, depending on how you respond to treatment.

The total length of treatment varies significantly between individuals. Some people show improvement after the first few infusions, while others require the full induction course before noticing changes in their mood or symptoms. Your doctor will reassess your progress after the induction phase and decide whether to continue with maintenance sessions, adjust the frequency, or modify your treatment plan.

If you respond well to ketamine, maintenance infusions may continue for months or longer. There is no fixed endpoint — treatment continues as long as it remains effective and you and your doctor agree it is beneficial. If you stop responding to the infusions, your doctor may recommend discontinuing treatment or exploring other options.

Cost and insurance coverage

Greenbrook's ketamine infusions are not covered by most insurance plans, though coverage varies by insurer and plan type. Some plans may cover a portion of the cost if ketamine is prescribed for treatment-resistant depression and certain criteria are met, but this is not standard. You will need to contact Greenbrook directly and provide your insurance information to learn whether your plan covers any part of the treatment.

Out-of-pocket costs for ketamine infusions at Greenbrook vary by location and the number of sessions you receive. A single infusion typically costs between several hundred and over a thousand dollars, depending on the clinic's pricing and your region. The full induction course of 6 infusions can cost several thousand dollars total. Greenbrook may offer payment plans or financing options, which you can discuss during your initial consultation.

Before starting treatment, ask Greenbrook for a detailed cost estimate based on your proposed treatment plan. Request an itemized breakdown showing the cost per infusion, any facility fees, and charges for monitoring or recovery time. This allows you to understand the total financial commitment before you begin.

Finding a Greenbrook location near you

Greenbrook TMS NeuroHealth operates clinics in multiple states, but not all regions have a location. You can search for nearby clinics on Greenbrook's website by entering your zip code or city. The search tool shows which locations are currently accepting new patients and provides contact information for each clinic.

If no Greenbrook clinic is within a reasonable distance, you have other options for ketamine infusion therapy. Other medical providers, hospitals, and specialized ketamine clinics also offer infusion treatment in many areas. Your primary care doctor or psychiatrist can refer you to providers in your region if Greenbrook is not available to you.

Availability at Greenbrook clinics can change, as some locations may temporarily stop accepting new patients during periods of high demand. Contacting the clinic directly is the most reliable way to learn current availability and to schedule an initial consultation.

What to bring and how to prepare

Before your first appointment, gather your medical records, including a list of all medications and supplements you currently take. Bring your insurance card and photo identification. If you have had previous psychiatric evaluations or psychological testing, those records can be helpful for the Greenbrook clinician to review.

On the day of your infusion, wear comfortable clothing and avoid eating a large meal when ready beforehand — your doctor will provide specific fasting instructions. Arrange your transportation in advance so you know how you will get home after your appointment. Plan to have someone available to pick you up, or pre-book a rideshare service.

Avoid alcohol and recreational drugs for at least 24 hours before your infusion. If you take any medications that interact with ketamine, your doctor will advise you on whether to adjust your schedule. Do not stop taking psychiatric medications without consulting your Greenbrook doctor first, as abrupt changes can affect your treatment response.

Comparing Greenbrook to other ketamine delivery methods

Greenbrook's in-office infusion model differs from other ways ketamine is delivered for depression treatment. Ketamine nasal spray (Esketamine, marketed as Spravato) is administered at a clinic but requires fewer total visits — typically one to three per week for four weeks, then maintenance every week or every other week. Oral ketamine, available through some specialized clinics, is taken at home but is less commonly used and has less research supporting its effectiveness.

Infusion therapy like Greenbrook's allows for precise dosing and close medical monitoring, which some research suggests may lead to faster symptom relief. The trade-off is that infusions require more time commitment per session and more frequent clinic visits during the induction phase. Nasal spray requires fewer visits but may take longer to show results and involves a different administration method.

The choice between Greenbrook infusions and other ketamine delivery methods depends on your schedule, insurance coverage, symptom severity, and what your doctor recommends. If you are considering ketamine treatment, discuss all available options with a psychiatrist or mental health provider in your area.

Frequently Asked Questions

Do I need a referral from my doctor to contact Greenbrook?

No referral is required to call Greenbrook and schedule a consultation. However, Greenbrook will want to review your psychiatric history and current treatment, so having records from your psychiatrist or therapist available is helpful. If you do not currently have a mental health provider, Greenbrook can work with you to gather the necessary medical information during your initial visit.

What happens if ketamine infusions do not work for me?

If you do not see improvement after completing the induction phase, your Greenbrook doctor will discuss next steps with you. Options may include adjusting the dosage or frequency of infusions, trying a different ketamine delivery method, or exploring other treatment approaches. Ketamine does not work for everyone, and your doctor can help you identify alternative treatments if needed.

Can I continue taking my regular antidepressant while receiving ketamine infusions?

In most cases, yes — you can continue taking your current psychiatric medications while receiving ketamine infusions. Your Greenbrook doctor will review all your medications and may adjust dosages or timing to avoid interactions. Never stop or change your medications without consulting your Greenbrook clinician first.

How long does improvement last after ketamine infusions?

Some people experience symptom relief that lasts weeks or months after completing infusions, while others need ongoing maintenance sessions to sustain improvement. The duration varies widely between individuals and depends on factors like the severity of your depression and how your brain responds to ketamine. Your doctor will monitor your progress and recommend a maintenance schedule based on how long your improvement lasts.

What if I miss an infusion appointment?

Contact Greenbrook as soon as possible to reschedule. Missing appointments can affect your treatment timeline and may delay your progress. Greenbrook can work with you to find alternative appointment times, though availability depends on the clinic's schedule and current patient load.